"Nano" drug that prevents kidney toxicity

     The main problem of drugs taken orally is that their distribution can not be specific, that is, it flows through the system of the body through the bloodstream. Once a drug passes from the stomach into the intestines, it goes to the liver and then to the rest of the body through the bloodstream. This causes toxicity to the kidneys when ingested because the drugs slow down the kidney function, causing high levels of substances in the blood, that should be eliminated by the kidneys. To prevent kidney toxicity a "nano" drug that prevents the drug from reaching the kidneys was created.

     Researchers at the Complutense University of Madrid with other scientists have designed a "nano" drug to prevent kidney toxicity. This is possible because when ingested  it accumulates in the spleen, liver and lung. One of the authors of this research, Dolores R. Serrano, indicates that it is ideal to get the greatest possible amount of drug to the "target" organs to reduce this way the amount in places where it produce toxicity. The creation of the "nano" drug was achieved using nanoparticles GCPQ (˂250 nanometers). There are incorporated antifungal drug amphotericin B to these nanoparticles, which are used to treat certain conditions intravenously, being that orally it is toxic to other organs.

     An important advantage of this "nano" drug is preventing hospitalization and adverse effects caused by administering a drug intravenously. This is a very positive aspect, as there are patients who can not stand needles, just like hospitalization is also of little liking. This "nano" drug can be administered with any drug without affecting the kidneys, which is excellent news, because the kidneys have an important function in our body: eliminates toxic agents and recover the nutrients our body needs to regulate internal fluids.

Credits:

http://www.agenciasinc.es/Noticias/Disenan-un-nanomedicamento-oral-que-evita-la-toxicidad-en-los-rinones

Image: 

http://www.catalunyavanguardista.com/catvan/wp-content/uploads/2015/04/nanomedicamento_edited-1728x800_c.jpg